Search results for "Chemical design"
showing 9 items of 9 documents
Smart inulin-based polycationic nanodevices for siRNA delivery
2017
The advances of short interfering RNA (siRNA) mediated therapy provide a powerful option for the treatment of many diseases by silencing the expression of targeted genes including cancer development and progression. Inulin is a very simple and biocompatible polysaccharide proposed by our groups to produce interesting delivery systems for Nucleic Acid Based Drugs (NABDs), such as siRNA, either as polycations able to give polyplexes and polymeric coatings for nanosystems having a metallic core. In this research field, different functionalizing groups were linked to the inulin backbone with specific aims including oligoamine such as Ethylendiammine (EDA), Diethylediamine (DETA), Spermine, (SPM…
Data mining, dashboards and statistics: a powerful framework for the chemical design of molecular nanomagnets
2021
Abstract Three decades of intensive research in molecular nanomagnets have brought the magnetic memory in molecules from liquid helium to liquid nitrogen temperature. The enhancement of this operational temperature relies on a wise choice of the magnetic ion and the coordination environment. However, serendipity, oversimplified theories and chemical intuition have played the main role. In order to establish a powerful framework for statistically driven chemical design, we collected chemical and physical data for lanthanide-based nanomagnets to create a catalogue of over 1400 published experiments, developed an interactive dashboard (SIMDAVIS) to visualise the dataset, and applied inferentia…
Materials for molecular electronics and magnetism
2021
Functional molecular materials exhibiting, in particular, electrical, magnetic or optical properties have been an active focus of research over the last 50 years. These materials have been a source of inspiration in two interrelated areas of research, namely, molecular electronics and molecular magnetism, with important implications in biomedical areas. This themed issue highlights recent progress and perspectives in these important areas of materials science. The issue covers topics from the chemical design and manipulation of novel molecular materials with unprecedented control over their properties, even at the single-molecule level, to exciting applications of these special molecular sy…
Magnetic functionalities in MOFs: from the framework to the pore
2017
In this review, we show the different approaches so far developed to prepare Metal-Organic Frameworks (MOFs) presenting electronic functionalities, with particular attention to magnetic properties. We will cover the chemical design of the framework necessary for the incorporation of different magnetic phenomena, as well as the encapsulation of functional species in the pores leading to hybrid multifunctional MOFs combining an extended lattice with a molecular lattice.
Hybrid Materials Based on Magnetic Layered Double Hydroxides: A Molecular Perspective
2015
Design of functional hybrids lies at the very core of synthetic chemistry as it has enabled the development of an unlimited number of solids displaying unprecedented or even improved properties built upon the association at the molecular level of quite disparate components by chemical design. Multifunctional hybrids are a particularly appealing case among hybrid organic/inorganic materials. Here, chemical knowledge is used to deploy molecular components bearing different functionalities within a single solid so that these properties can coexist or event interact leading to unprecedented phenomena. From a molecular perspective, this can be done either by controlled assembly of organic/inorga…
Hybrid magnetic superconductors formed by TaS2 layers and spin crossover complexes.
2013
The restacking of charged TaS2 nanosheets with molecular counterparts has so far allowed for the combination of superconductivity with a manifold of other molecule-intrinsic properties. Yet, a hybrid compound that blends superconductivity with spin crossover switching has still not been reported. Here we continue to exploit the solid-state/molecule-based hybrid approach for the synthesis of a layered TaS2-based material that hosts Fe(2+) complexes with a spin switching behavior. The chemical design and synthetic aspects of the exfoliation/restacking approach are discussed, highlighting how the material can be conveniently obtained in the form of highly oriented easy-to-handle flakes. Finall…
ChemInform Abstract: Hybrid Materials Based on Magnetic Layered Double Hydroxides: A Molecular Perspective
2015
ConspectusDesign of functional hybrids lies at the very core of synthetic chemistry as it has enabled the development of an unlimited number of solids displaying unprecedented or even improved properties built upon the association at the molecular level of quite disparate components by chemical design. Multifunctional hybrids are a particularly appealing case among hybrid organic/inorganic materials. Here, chemical knowledge is used to deploy molecular components bearing different functionalities within a single solid so that these properties can coexist or event interact leading to unprecedented phenomena. From a molecular perspective, this can be done either by controlled assembly of orga…
Coexistence of superconductivity and magnetism by chemical design.
2010
Although the coexistence of superconductivity and ferromagnetism in one compound is rare, some examples of such materials are known to exist. Methods to physically prepare hybrid structures with both competing phases are also known, which rely on the nanofabrication of alternating conducting layers. Chemical methods of building up hybrid materials with organic molecules (superconducting layers) and metal complexes (magnetic layers) have provided examples of superconductivity with some magnetic properties, but not fully ordered. Now, we report a chemical design strategy that uses the self assembly in solution of macromolecular nanosheet building blocks to engineer the coexistence of supercon…
Chemical design of coordination polymers and functional materials: from pore control in MOFs through spin dynamics in nanomagnets to rotaxanes in mol…
2022
El trabajo de esta tesis se enmarca en el diseño químico de polímeros de coordinación y de materiales funcionales para poder ser utilizados en el campo de los materiales moleculares. El capítulo 1 ofrece una visión de los avances más significativos en la química de coordinación, así como una introducción general de los materiales moleculares más relevantes en la actualidad. El objetivo es proporcionar al lector el conocimiento necesario para establecer las bases sobre los campos a tratar. El resto de capítulos está organizado de acuerdo con un aumento de la dimensionalidad, empezando con moléculas discretas y terminando con polímeros de coordinación. El capítulo dos describe dos estructuras…